| 1 | Arkansas State over Texas State 77–31 · at home · 2023-11-18 | 2023 | +3.2 | +49.2 | 42% | — |
| 2 | South Florida over Syracuse 45–0 · neutral site · 2023-12-22 | 2023 | +4.2 | +49.2 | 40% | — |
| 3 | New Mexico State over Auburn 31–10 · on the road · 2023-11-18 | 2023 | +25 | +46.0 | 6% | — |
| 4 | Arizona over #19Washington State 44–6 · on the road · 2023-10-14 | 2023 | +7.5 | +45.5 | 32% | 11 |
| 5 | Florida Atlantic over South Florida 56–14 · on the road · 2023-10-14 | 2023 | +2.5 | +44.5 | 44% | — |
| 6 | UCF over #15Oklahoma State 45–3 · at home · 2023-11-11 | 2023 | +2.5 | +44.5 | 44% | 15 |
| 7 | Auburn over Arkansas 48–10 · on the road · 2023-11-11 | 2023 | +2.5 | +40.5 | 44% | — |
| 8 | Texas State over Baylor 42–31 · on the road · 2023-09-02 | 2023 | +27 | +38.0 | 5% | — |
| 9 | Army over #17Air Force 23–3 · neutral site · 2023-11-04 | 2023 | +18 | +38.0 | 13% | 13 |
| 10 | California over UCLA 33–7 · on the road · 2023-11-26 | 2023 | +9.5 | +35.5 | 28% | — |
| 11 | Rice over Tulsa 42–10 · on the road · 2023-10-19 | 2023 | +3 | +35.0 | 43% | — |
| 12 | Hawai'i over Air Force 27–13 · at home · 2023-11-12 | 2023 | +20.5 | +34.5 | 10% | — |
| 13 | Duke over #9Clemson 28–7 · at home · 2023-09-05 | 2023 | +12.5 | +33.5 | 22% | 21 |
| 14 | South Alabama over Oklahoma State 33–7 · on the road · 2023-09-16 | 2023 | +7 | +33.0 | 33% | — |
| 15 | Bowling Green over Georgia Tech 38–27 · on the road · 2023-09-30 | 2023 | +22 | +33.0 | 8% | — |
| 16 | Coastal Carolina over Marshall 34–6 · at home · 2023-10-28 | 2023 | +3.5 | +31.5 | 41% | — |
| 17 | Kansas over UCF 51–22 · at home · 2023-10-07 | 2023 | +2 | +31.0 | 45% | — |
| 18 | #16Missouri over #14Tennessee 36–7 · at home · 2023-11-11 | 2023 | +2 | +31.0 | 45% | 2 |
| 19 | App State over Georgia State 42–14 · on the road · 2023-11-11 | 2023 | +2.5 | +30.5 | 44% | — |
| 20 | New Mexico over Fresno State 25–17 · on the road · 2023-11-19 | 2023 | +22.5 | +30.5 | 8% | — |
| 21 | Fresno State over New Mexico State 37–10 · neutral site · 2023-12-16 | 2023 | +3 | +30.0 | 43% | — |
| 22 | Georgia Tech over Virginia 45–17 · on the road · 2023-11-04 | 2023 | +1.5 | +29.5 | 46% | — |
| 23 | Navy over UAB 31–6 · at home · 2023-11-11 | 2023 | +3.5 | +28.5 | 41% | — |
| 24 | Virginia over #10North Carolina 31–27 · on the road · 2023-10-21 | 2023 | +24 | +28.0 | 7% | 20 |
| 25 | Arkansas State over Louisiana 37–17 · at home · 2023-11-04 | 2023 | +7 | +27.0 | 33% | — |
| 26 | Fordham over Buffalo 40–37 · on the road · 2023-09-09 | 2023 | +23.5 | +26.5 | 7% | — |
| 27 | Buffalo over Central Michigan 37–13 · at home · 2023-10-07 | 2023 | +2.5 | +26.5 | 44% | — |
| 28 | Northwestern over Wisconsin 24–10 · on the road · 2023-11-11 | 2023 | +12 | +26.0 | 23% | — |
| 29 | Arkansas State over Massachusetts 52–28 · on the road · 2023-09-30 | 2023 | +1.5 | +25.5 | 46% | — |
| 30 | Iowa State over Cincinnati 30–10 · on the road · 2023-10-14 | 2023 | +5 | +25.0 | 38% | — |
| 31 | Georgia State over Utah State 45–22 · neutral site · 2023-12-23 | 2023 | +1.8 | +24.8 | 46% | — |
| 32 | Louisiana over South Alabama 33–20 · on the road · 2023-10-28 | 2023 | +11.5 | +24.5 | 24% | — |
| 33 | UAB over South Florida 56–35 · at home · 2023-10-07 | 2023 | +3 | +24.0 | 43% | — |
| 34 | Pittsburgh over #14Louisville 38–21 · at home · 2023-10-14 | 2023 | +7 | +24.0 | 33% | 16 |
| 35 | Arizona State over UCLA 17–7 · on the road · 2023-11-12 | 2023 | +14 | +24.0 | 19% | — |
| 36 | Colorado over #17TCU 45–42 · on the road · 2023-09-02 | 2023 | +20.8 | +23.8 | 10% | 13 |
| 37 | Sam Houston over Louisiana Tech 42–27 · on the road · 2023-11-11 | 2023 | +8.5 | +23.5 | 30% | — |
| 38 | #8Florida State over #5LSU 45–24 · neutral site · 2023-09-03 | 2023 | +2.2 | +23.2 | 44% | 3 |
| 39 | Utah State over Colorado State 44–24 · at home · 2023-10-08 | 2023 | +3 | +23.0 | 43% | — |
| 40 | UCLA over USC 38–20 · on the road · 2023-11-18 | 2023 | +5 | +23.0 | 38% | — |
| 41 | New Mexico over Hawai'i 42–21 · at home · 2023-10-21 | 2023 | +1.5 | +22.5 | 46% | — |
| 42 | East Carolina over Florida Atlantic 22–7 · on the road · 2023-11-11 | 2023 | +7.5 | +22.5 | 32% | — |
| 43 | Boston College over #22SMU 23–14 · neutral site · 2023-12-28 | 2023 | +13.5 | +22.5 | 20% | 8 |
| 44 | Louisiana over UAB 41–21 · on the road · 2023-09-16 | 2023 | +2 | +22.0 | 45% | — |
| 45 | Troy over Georgia State 28–7 · on the road · 2023-09-30 | 2023 | +1 | +22.0 | 48% | — |
| 46 | Georgia Tech over #17Miami 23–20 · on the road · 2023-10-08 | 2023 | +19 | +22.0 | 12% | 13 |
| 47 | Maryland over Auburn 31–13 · neutral site · 2023-12-30 | 2023 | +4 | +22.0 | 40% | — |
| 48 | Miami (OH) over Ohio 30–16 · on the road · 2023-10-28 | 2023 | +7.5 | +21.5 | 32% | — |
| 49 | NC State over North Carolina 39–20 · at home · 2023-11-26 | 2023 | +2.5 | +21.5 | 44% | — |
| 50 | Ohio over Georgia Southern 41–21 · neutral site · 2023-12-16 | 2023 | +1.5 | +21.5 | 46% | — |
| 51 | Miami (OH) over Cincinnati 31–24 · on the road · 2023-09-16 | 2023 | +14.2 | +21.2 | 19% | — |
| 52 | Boston College over Georgia Tech 38–23 · on the road · 2023-10-21 | 2023 | +6 | +21.0 | 35% | — |
| 53 | Temple over Navy 32–18 · at home · 2023-11-04 | 2023 | +7 | +21.0 | 33% | — |
| 54 | Purdue over Minnesota 49–30 · at home · 2023-11-11 | 2023 | +1.5 | +20.5 | 46% | — |
| 55 | San Diego State over Fresno State 33–18 · at home · 2023-11-26 | 2023 | +5.5 | +20.5 | 37% | — |
| 56 | Memphis over Iowa State 36–26 · on the road · 2023-12-29 | 2023 | +10.5 | +20.5 | 26% | — |
| 57 | Central Michigan over South Alabama 34–30 · on the road · 2023-09-23 | 2023 | +16 | +20.0 | 16% | — |
| 58 | Northwestern over Maryland 33–27 · at home · 2023-10-28 | 2023 | +14 | +20.0 | 19% | — |
| 59 | Oklahoma State over Kansas State 29–21 · at home · 2023-10-06 | 2023 | +11.5 | +19.5 | 24% | — |
| 60 | Arizona over #20UCLA 27–10 · at home · 2023-11-05 | 2023 | +2.5 | +19.5 | 44% | 10 |